Glyoxal in medicine

Glyoxal is of great use in the pharmaceutical industry.

Technical grade glyoxal appearance

Pharmaceuticals and chemical industry glyoxal and ammonia can be synthesized imidazole, methyl imidazole, used for the production of clotrimazole and other antibiotics; glyoxal and 2-aminobutanol condensation, generate aldimine, and then reduced to obtain ethambutol , is a highly efficient M. tuberculosis inhibitor; glyoxal reacts with o-phenylenediamine to form quinoline (oral + oxaline), a synthetic raw material for the treatment of tuberculosis drug pyrazinamide; condensation reaction of glyoxal with glycine amide The production of 2-hydroxypyrazine can further produce sulfa drugs and insecticides. Glyoxal is an important organic intermediate for the synthesis of glyoxylic acid, glyoxylic acid is a relatively tight organic intermediate in recent years. It is mainly used for preparing p-hydroxyphenylglycine (a side chain compound of broad-spectrum antibiotic amoxycillin), p-hydroxyphenylacetic acid (an intermediate of anti-hypertensive agent atenolol), allantoin (skin wound healing agent and cosmetics) Additives) etc.

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